Microglia and Central Sensitization Syndrome: A New Paradigm for Understanding and Treating Chronic Pain and Depression
Chronic pain and chronic neuropsychiatric illness frequently occur together and when they do so are highly treatment resistant. These conditions share a common neurophysiology and are neuroinflammatory conditions. Recent research has focused on microglia as the mediator of this inflammatory process. This lecture will discuss the research on the neurobiology of microglia and their role in the occurrence of central sensitization. Emphasis will be on the clinical implications and application of this research.
Faculty: Gary E. Kaplan, DO, DABFP, DABPM, FAAMA
This 1-hour CME activity is designed for all clinicians who treat chronic pain.
Upon completion of this activity, participants should be better able to:
- Discuss the events that cause up regulation of microglia.
- Define central sensitization as distinguished from central sensitization syndrome.
- Discuss the common neurophysiology of chronic pain and depression.
- Discuss a comprehensive approach to the treatment of chronic pain and depression that targets microglia activation.
Gary E. Kaplan, DO, DABFP, DABPM, FAAMA, is the founder and medical director of Kaplan Center for Integrative Medicine. Dr. Kaplan is a clinical associate professor in the Department of Community and Family Medicine at Georgetown University School of Medicine. A pioneer and leader in the field of integrative medicine, Dr. Kaplan is board-certified in family medicine, pain medicine, and medical acupuncture.
Staff and Content Validation Reviewer Disclosures
The staff involved with this activity and any content validation reviewers of this activity have reported no relevant financial relationships with commercial interests.
Planning Committee/Faculty Disclosure
Dr. Kaplan reports that he has nothing to disclose.
Debra Nelson-Hogan, Director of Education for the Academy of Integrative Pain Management, reports that she has nothing to disclose.
Cathleen Coneghen, Assistant Director of Education for the Academy of Integrative Pain Management, reports that she has nothing to disclose.
The information provided at this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a health care provider relative to diagnostic and treatment options of a specific patient’s medical condition.
For questions regarding CME for this activity, you may reach the department of education at the Academy of Integrative Pain Management at email@example.com.
For successful completion of this activity, please complete a pre-test; utilize the audio recordings synched with the presentation slides to review the content, providing answers to your questions as necessary; and complete a post-test and evaluation following the activity. You will then be prompted to print your certificate. This activity should take approximately 60 minutes to complete.
This program is accredited for physicians, nurses, and psychologists. All other clinicians can submit the certificate of attendance upon completion of the program to their licensing boards for consideration of credit.
The American Academy of Pain Management is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The American Academy of Pain Management designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
The American Academy of Pain Management is approved by the California Board of Registered Nursing, Provider Number CEP 15881 for 1 contact hour.
The American Academy of Pain Management is approved by the American Psychological Association to sponsor continuing education for psychologists. The American Academy of Pain Management maintains responsibility for this program and its content.
The Academy designates this activity for a maximum of 1 CE credit.
- 1.00 AMA PRA Category 1 Credit(s)™
- 1.00 APA
- 1.00 Document of Attendance
- 1.00 Nursing Credit