Low Risk, High Success: Prolotherapy Regenerative Medicine for Osteoarthritis

Osteoarthritis is a common condition, affecting over 30 million adults in the U.S. alone. Insufficient healing of ligament or tendon connective tissue surrounding a joint is believed by some medical researchers to be the most important factor in the later development of osteoarthritis. Prolotherapy is a nonsurgical regenerative injection treatment that stimulates healing of joint connective tissue and may also promote cartilage regeneration. It is low risk, with a high success rate. This program discusses the science and studies supporting the three prolotherapy formulas—traditional dextrose, platelet-rich plasma (PRP), and biocellular (stem cell)—and how prolotherapy works to reduce or eliminate pain.     

Faculty: Donna D. Alderman, DO

Target Audience

This .5-hour CE activity is designed for all clinicians who treat chronic pain. 

Learning Objectives

Upon completion of this activity, participants should be better able to:

  1. Explain the most common etiology of osteoarthritis
  2. Discuss what is prolotherapy, its history, and how it has evolved
  3. Discuss the different forms of prolotherapy regenerative medicine and how and why each works to treat joint osteoarthritis

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AIPM does not share your personal information provided to this site with any third party, except where required by CE governing bodies for verification of CE activities. Your email address will only be used to contact you in relation to your activities on the website.

The information provided in this activity is for continuing education purposes only and is not meant to subsitute for the independent medical judgement of a health care provider relative to diagnostic and treatment options of a specific patient's medical condition.

Presentations used with permission. Copyright © Academy of Integrative Pain Management 2018

For questions regarding CME for this activity, you may reach the department of education at the Academy of Integrative Pain Management at education@integrativepain.org.


Course summary
Available credit: 
  • 0.50 ACPE
  • 0.50 AMA PRA Category 1 Credit(s)™
  • 0.50 ANCC
  • 0.50 Document of Attendance
Course opens: 
Course expires: 

Donna D. Alderman, DO, is an osteopathic physician and an expert in musculoskeletal and orthopedic regenerative medicine. She is a graduate of Cornell University, Ithaca, New York, and Western University of Health Sciences, Pomona, California, and is board certified in prolotherapy and integrative medicine. Dr. Alderman has authored multiple medical journal articles and textbook chapters on traditional prolotherapy, platelet-rich plasma (PRP) prolotherapy, and biocellular (stem/stromal cell) prolotherapy—all nonsurgical treatments for chronic pain, osteoarthritis, and sports injuries. She has practiced prolotherapy since 1996 and is a frequent lecturer for multiple physician educational organizations and colleges. Dr. Alderman is medical director of the Hemwall Centers for Orthopedic Regenerative Medicine, with two offices in California.

Disclosure of Conflict of Interest

All individuals in a position to control the content who had relevant financial relationships are listed below. If their name is not listed below, they disclosed that they had no relevant financial relatioships.

Dr. Alderman reports that she has nothing to disclose.

Acknowledgement of Commercial Support
No commercial support was received for this educational activity.


Method of Learner Participation: Each learner will listen to each audio self-directed module while following along with the visual slides. Upon completion, each learner will answer evaluation questions to receive their certificate.

Satisfactory Completion: Learners must complete an evaluation to receive a certificate of completion. Your chosen sessions/videos must be viewed in their entirety.

Bibliographic Sources: Bibliographic sources can be found on the program slides.

The Academy of Integrative Pain Management is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The Academy of Integrative Pain Management designates this live activity for a maximum of .5 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
The American Osteopathic Association accepts ACCME accredited programs for Category 2-A CME credit.

Nurses and Pharmacists
In support of improving patient care, this activity has been planned and implemented by Amedco, LLC and the Academy of Integrative Pain Management. Amedco, LLC is jointly accredited by the American Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. Amedco designates this enduring material activity for a maximum of .5 contact hour for nurses and .5 knowldege-based contact hour for pharmacists. Learners should claim only the credit commensurate with the extrent of their participation in the activity. PHARMACIST NOTE: The only offiical Statement of Credit is the one you pull from CPE Monitor. 

Nurse Practitioners
The American Association of Nurse Practitioners (AANP) recognizes the Accreditation Council for Continuing Medical Education (ACCME) and the American Nurses Credentialing Center (ANCC) as approved accreditors and allow reciprocity for AANPCP continuing education credit.

Available Credit

  • 0.50 ACPE
  • 0.50 AMA PRA Category 1 Credit(s)™
  • 0.50 ANCC
  • 0.50 Document of Attendance

Accreditation Period

Course opens: 
Course expires: 


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